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Uruguayan Medical Journal

ISSN: 1688-0390

Vol.32 - Nº 1 - Abr. 2016

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Techniques and measures geared to reducing bleeding and the consumption of hemocomponents in liver transplant. Evaluation of the first two years at the Bi-Institutional Transplant Unit in the Transfusion Medicine and Hemotherapy specialization. Results of the participation of the Transfusion Medicine Department on the indicatio of deplasmatized bloodduring heart surgery preoperative period.

Rev Med Urug 2016; 32: 8-18
Full text (spanish) |  Full text (spanish) (New windows, pdf) | Abstract


Introduction: liver transplant is the only final treatment for chronic terminal liver disease and other conditions that have no alternative therapies. Bleeding and the hemocomponents consumption has been associated to reduction of graft survival and patient.

Objective: to evaluate results in hemocomponents consumption with the application of measures and techniques that aim to minimize bleeding. To estimate survival time.

Method: descriptive, observational, retrospective study of the first 31 patients who had undergone liver transplant. A chi square test was used to find the qualitative variables association, significance level α = 0.05, the Kaplan Meyer test was used to analyse survival.

Results: a score was designed to analyse hemocomponent consumption, no deplasmatized blood units were transfused in 5 patients (16.1%), and 1 to 4 deplasmatized blood units were consumed in 58.1%, with a 3.7 ± 0.6 average. A single patient (3.2%) was transplanted with no hemocomponent transfusion.

Upon six months, survival represents 81.3%, with a total of five events, 26 patients being alive towards the end of the study.

Conclusions: measures to diminish bleeding and transfusion requirements were effective. Results were acceptable, similar to those published globally.